Clinical features and basic mechanisms of quinidine-induced arrhythmias
نویسندگان
چکیده
منابع مشابه
Basic mechanisms of cardiac impulse propagation and associated arrhythmias.
Propagation of excitation in the heart involves action potential (AP) generation by cardiac cells and its propagation in the multicellular tissue. AP conduction is the outcome of complex interactions between cellular electrical activity, electrical cell-to-cell communication, and the cardiac tissue structure. As shown in this review, strong interactions occur among these determinants of electri...
متن کاملEvaluation of propranolol and quinidine in the treatment of quinidine-resistant arrhythmias.
From the University of Michigan Medical Center, Ann Arbor, Mich. This work was supported by Grants from the Michigan Heart Association and U.S. Public Health Service, National Institutes of Health HE 07406-05. Manuscript received October 3, 1969, accepted February 6, 1970. Address for reprints: Ernest W. Reynolds, Jr., MD, University of Michigan Medical Center, Ann Arbor, Mich. 48104. Combining...
متن کاملBasic Science for the Clinical Electrophysiologist Cardiac Metabolism and Arrhythmias
Sudden cardiac death remains a leading cause of death in the Western world, accounting for up to 20% of all deaths in the United States1,2 The major causes of sudden cardiac death in adults age 35 and older are coronary artery disease (70% to 80%) and dilated cardiomyopathy (10% to 15%).3 At the molecular level, a wide variety of mechanisms contribute to arrhythmias that cause sudden cardiac de...
متن کاملClinical Features and Pathogenetic Mechanisms
Spinocerebellar Ataxia 12 (SCA12) is a rare disease that was first identified in a family in the United States. Patients suffered from classical spinocerebellar ataxia symptoms with an age of disease onset ranging from 8-55 years. A trinucleotide (CAG) repeat expansion was confirmed in all the affected individuals. The CAG expansion mapped to the 5’ untranslated region (UTR) of the PPP2R2B gene...
متن کاملKindling: basic mechanisms and clinical validity.
The Federation has produced a considerable number of reports, assessments, guidelines, standards , recommendations and similar printed products. These have covered technology, education, science, and clinical practice topics. These were generally the product of Federation committees commissioned by the Executive Committee and the General Assembly. All were reviewed by the Executive Committee an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1986
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(86)80032-8